- Tangtse has been an important waypoint for centuries, lying on the traditional trade route between Leh and the Tibetan plateau.
- Historically, it was part of the larger Silk Route network and a halting station for caravans moving toward Tibet and Central Asia.
- The village has also played a role in military history, particularly during the Indo-China conflicts in the 1960s.
- Tangtse Monastery, although small, is historically significant and affiliated with the Gelugpa school of Tibetan Buddhism.
